{"id":8858,"date":"2026-09-29T15:26:50","date_gmt":"2026-09-29T15:26:50","guid":{"rendered":"https:\/\/www.rbc.com\/en\/thought-leadership\/?p=8858"},"modified":"2026-09-29T15:26:51","modified_gmt":"2026-09-29T15:26:51","slug":"canadas-biotech-challenge","status":"publish","type":"post","link":"https:\/\/www.rbc.com\/en\/thought-leadership\/ai-technology-and-innovation\/canadas-biotech-challenge\/","title":{"rendered":"Canada&#8217;s Biotech Challenge"},"content":{"rendered":"\n<div\n\tid=\"tl-fpb-1\"\n\tstyle=\"background-image:url(https:\/\/www.rbc.com\/en\/thought-leadership\/wp-content\/uploads\/sites\/27\/2026\/09\/Disruptors-S11-WEB-BANNER-EP4_Banner-wide-copy-2.jpg?quality=80&amp;w=4096);background-position:50% 50%;background-size:cover;min-height:500px\" class=\"tl-featured-post-banner wp-block-rbc-thought-leadership-blocks-featured-post-banner\">\n\t\t\t<div class=\"tl-featured-post-banner__gradient\" style=\"position:absolute;top:0;left:0;right:0;bottom:0;z-index:0;pointer-events:none;\"><\/div>\n\t\n\t<div class=\"tl-featured-post-banner__inner\">\n\t\t\t\t<a\n\t\t\tclass=\"tl-pill tl-pill--banner\"\n\t\t\thref=\"https:\/\/www.rbc.com\/en\/thought-leadership\/ai-technology-and-innovation\"\n\t\t>\n\t\t\tAI, Technology and Innovation\t\t<\/a>\n\t\t\n\t\t<div class=\"tl-featured-post-banner__content\">\n\t\t\t\t\t\t<h2 class=\"tl-featured-post-banner__title\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.rbc.com\/en\/thought-leadership\/ai-technology-and-innovation\/canadas-biotech-challenge\/\">\n\t\t\t\t\t\tCanada&#8217;s Biotech Challenge\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/h2>\n\t\t\t\n\t\t\t\t\t\t<p class=\"tl-featured-post-banner__excerpt\">\n\t\t\t\tCanadian medical research has produced breakthrough after breakthrough. But too often, the companies behind the science scale elsewhere.\t\t\t<\/p>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<section class=\"wp-block-rbc-section-block  pos-rel\" style=\"border-radius:0px\">\n<div class=\"wp-block-rbc-section-inner-block  section-inner\" style=\"border-radius:0x\">\n<div style=\"width:100%;height:200px\" class=\"wp-block-rbc-rbc-iframe mar-b-hlf mob-mar-b-hlf\"><iframe loading=\"lazy\" src=\"https:\/\/player.simplecast.com\/7784fa53-38f5-4a24-a0c1-6d4f38ad8d5f?dark=false\" width=\"100%\" height=\"100%\" style=\"border:none\" title=\"Iframe Embed\"><\/iframe><\/div>\n\n\n\n<p class=\"mar-t-hlf mob-mar-t-hlf wp-block-paragraph\">Listen on <a href=\"https:\/\/podcasts.apple.com\/ca\/podcast\/disruptors\/id1332711400\" target=\"_blank\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-6f1fbcd9\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"link click\" data-dig-label=\"Apple Podcasts\" rel=\"noreferrer noopener\" class=\"rbc-link-format\">Apple Podcasts<\/a>, <a href=\"https:\/\/open.spotify.com\/episode\/0HAOkPa4gnBySa9uN0wL2m?si=d4_tnlojRym7IIFNOPs5uA\" target=\"_blank\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-6f1fbcd9\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"link click\" data-dig-label=\"Spotify\" rel=\"noreferrer noopener\" class=\"rbc-link-format\">Spotify<\/a> or <a href=\"https:\/\/player.simplecast.com\/7784fa53-38f5-4a24-a0c1-6d4f38ad8d5f?dark=false\" target=\"_blank\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-6f1fbcd9\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"link click\" data-dig-label=\"Simplecast\" rel=\"noreferrer noopener\" class=\"rbc-link-format\">Simplecast<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Canadian medical research has produced breakthrough after breakthrough. But too often, the companies behind the science scale elsewhere, and the talent, revenue and ownership goes, too.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">On the latest episode of Disruptors, Clarissa Desjardins, co-founder and CEO of Montreal\u2019s Congruence Therapeutics, talks with host John Stackhouse about what it will take to change that, all while AI and China reshape drug discovery.<\/p>\n<\/div>\n<\/section>\n\n\n\n<section class=\"wp-block-rbc-section-block  pos-rel\" style=\"border-radius:0px\">\n<div class=\"wp-block-rbc-section-inner-block  section-inner\" style=\"border-radius:0x\">\n<h4 id=\"h-faqs\" class=\"wp-block-heading has-rbc-bright-blue-color has-text-color has-link-color wp-elements-1\">FAQs<\/h4>\n\n\n\n<div class=\"wp-block-rbc-rbc-collapsible-accordion accordion\" id=\"&quot;accordionSet1\">\n<div class=\"wp-block-rbc-rbc-collapsible-panel\"><div class=\"accordion-panel\"><button id=\"accordion-title6aa0c23d\" class=\"collapse-toggle collapsed\" data-target=\"#accordion6aa0c23d\" data-toggle=\"collapse\" data-parent=\"#accordionSet1\" aria-expanded=\"false\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-6aa0c23d\" aria-controls=\"accordion6aa0c23d\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"collapsible closed\" data-dig-label=\"&lt;strong&gt;&lt;strong&gt;Who is Clarissa Desjardins?&lt;\/strong&gt;&lt;\/strong&gt;\" action-closed=\"collapsible closed\" action-opened=\"collapsible open\"><div><strong><strong>Who is Clarissa Desjardins?<\/strong><\/strong><\/div><\/button><div class=\"collapse-content collapse\" id=\"accordion6aa0c23d\" role=\"region\" aria-labelledby=\"accordion-title6aa0c23d\"><div class=\"collapse-inner\">\n<p class=\"wp-block-paragraph\">Clarissa Desjardins is a Montreal-based scientist and serial biotech entrepreneur, and co-founder and CEO of Congruence Therapeutics. Congruence is her fourth company. She previously founded Clementia Pharmaceuticals, co-founded Caprion Pharmaceuticals, and started her first company while completing a Ph.D.\u202fat the Montreal Neurological Institute.&nbsp;<\/p>\n<\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-rbc-rbc-collapsible-panel\"><div class=\"accordion-panel\"><button id=\"accordion-title217108c0\" class=\"collapse-toggle collapsed\" data-target=\"#accordion217108c0\" data-toggle=\"collapse\" data-parent=\"#accordionSet1\" aria-expanded=\"false\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-217108c0\" aria-controls=\"accordion217108c0\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"collapsible closed\" data-dig-label=\"What is Congruence Therapeutics?\" action-closed=\"collapsible closed\" action-opened=\"collapsible open\"><div><strong><strong><strong>What is Congruence Therapeutics?<\/strong><\/strong><\/strong><\/div><\/button><div class=\"collapse-content collapse\" id=\"accordion217108c0\" role=\"region\" aria-labelledby=\"accordion-title217108c0\"><div class=\"collapse-inner\">\n<p class=\"wp-block-paragraph\">Congruence Therapeutics is a clinical-stage biotechnology company that uses computational tools, including machine learning and protein-structure simulation, to discover small-molecule drugs. Its approach aims to reduce the trial and error of early drug discovery. Its first drug candidate is in clinical trials, with further programs expected to follow.<\/p>\n<\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-rbc-rbc-collapsible-panel\"><div class=\"accordion-panel\"><button id=\"accordion-titlef40086f9\" class=\"collapse-toggle collapsed\" data-target=\"#accordionf40086f9\" data-toggle=\"collapse\" data-parent=\"#accordionSet1\" aria-expanded=\"false\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-f40086f9\" aria-controls=\"accordionf40086f9\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"collapsible closed\" data-dig-label=\"What is the main issue discussed in this episode?\" action-closed=\"collapsible closed\" action-opened=\"collapsible open\"><div><strong><strong><strong>What is the main issue discussed in this episode?<\/strong><\/strong><\/strong><\/div><\/button><div class=\"collapse-content collapse\" id=\"accordionf40086f9\" role=\"region\" aria-labelledby=\"accordion-titlef40086f9\"><div class=\"collapse-inner\">\n<p class=\"wp-block-paragraph\">The episode examines the state of the global biotech industry\u2014which has seen China rapidly industrialize drug discovery and AI transform how drugs are found\u2014and Canada\u2019s place in it. Clarissa Desjardins and John Stackhouse discuss why Canada\u2019s strong scientific expertise has not translated into a burgeoning domestic industry, and what the country should do now.<\/p>\n<\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-rbc-rbc-collapsible-panel\"><div class=\"accordion-panel\"><button id=\"accordion-title31aa1f14\" class=\"collapse-toggle collapsed\" data-target=\"#accordion31aa1f14\" data-toggle=\"collapse\" data-parent=\"#accordionSet1\" aria-expanded=\"false\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-31aa1f14\" aria-controls=\"accordion31aa1f14\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"collapsible closed\" data-dig-label=\"Why does biotech matter for Canada?\" action-closed=\"collapsible closed\" action-opened=\"collapsible open\"><div><strong><strong>Why does biotech matter for Canada?<\/strong><\/strong><\/div><\/button><div class=\"collapse-content collapse\" id=\"accordion31aa1f14\" role=\"region\" aria-labelledby=\"accordion-title31aa1f14\"><div class=\"collapse-inner\">\n<p class=\"wp-block-paragraph\">The biotech industry provides economic growth and national resilience. As China becomes a major source of new drugs, Canada\u2019s ability to discover, develop and produce its own medicines is increasingly a question of sovereignty.<\/p>\n<\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-rbc-rbc-collapsible-panel\"><div class=\"accordion-panel\"><button id=\"accordion-title02f35f74\" class=\"collapse-toggle collapsed\" data-target=\"#accordion02f35f74\" data-toggle=\"collapse\" data-parent=\"#accordionSet1\" aria-expanded=\"false\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-02f35f74\" aria-controls=\"accordion02f35f74\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"collapsible closed\" data-dig-label=\"What is changing in the biotech industry?\" action-closed=\"collapsible closed\" action-opened=\"collapsible open\"><div><strong><strong>What is changing in the biotech industry?<\/strong><\/strong><\/div><\/button><div class=\"collapse-content collapse\" id=\"accordion02f35f74\" role=\"region\" aria-labelledby=\"accordion-title02f35f74\"><div class=\"collapse-inner\">\n<p class=\"wp-block-paragraph\">There are two shifts dominating: AI and computational tools are shortening early drug discovery, while China has built state-backed, round-the-clock drug discovery operations producing clinic-ready candidates efficiently. That changes the economics for North American biotech firms, and is pushing them toward novel technologies and harder-to-treat diseases.<\/p>\n<\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-rbc-rbc-collapsible-panel\"><div class=\"accordion-panel\"><button id=\"accordion-title549e12c0\" class=\"collapse-toggle collapsed\" data-target=\"#accordion549e12c0\" data-toggle=\"collapse\" data-parent=\"#accordionSet1\" aria-expanded=\"false\" data-dig-id=\"LP-AI,TechnologyandInnovation-8858-549e12c0\" aria-controls=\"accordion549e12c0\" data-dig-category=\"LP-AI,TechnologyandInnovation\" data-dig-action=\"collapsible closed\" data-dig-label=\"What should Canada do?\" action-closed=\"collapsible closed\" action-opened=\"collapsible open\"><div><strong><strong>What should Canada do?<\/strong><\/strong><\/div><\/button><div class=\"collapse-content collapse\" id=\"accordion549e12c0\" role=\"region\" aria-labelledby=\"accordion-title549e12c0\"><div class=\"collapse-inner\">\n<p class=\"wp-block-paragraph\">Desjardins argues Canada should mobilize more domestic capital, take more \u201cshots on goal\u201d with new companies, and improve R&amp;D tax credits and talent attraction. She wants Canadian investors to back companies through to global scale. John Stackhouse adds that biotech belongs in Canada\u2019s sovereignty agenda, supported by policy, capital and education.<\/p>\n<\/div><\/div><\/div><\/div>\n<\/div>\n<\/div>\n<\/section>\n<style class=\"advgb-styles-renderer\">@media (min-width:782px){#tl-fpb-1 .tl-featured-post-banner__gradient{background:linear-gradient(135deg, #070707, #00356300 100%);opacity:1;}}@media (max-width:781px){#tl-fpb-1{background-image:url(https:\/\/www.rbc.com\/en\/thought-leadership\/wp-content\/uploads\/sites\/27\/2026\/09\/Disruptors-S11-WEB-BANNER-EP4_Banner-wide-copy-2.jpg?quality=80&w=4096)!important;background-position:50% 50%!important;background-size:cover!important;min-height:400px!important;}#tl-fpb-1 .tl-featured-post-banner__gradient{background:linear-gradient(45deg, #070707, #00356300 100%);opacity:1;}}<\/style>","protected":false},"excerpt":{"rendered":"<p>Canadian medical research has produced breakthrough after breakthrough. But too often, the companies behind the science scale elsewhere.<\/p>\n","protected":false},"author":89,"featured_media":8891,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"disable_focal_point":true,"featured_image_focal_point":{"x":0.56,"y":0.51},"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","tl_feed_thumbnail":0,"tl_feed_thumbnail_focal_point":{"x":0.5,"y":0.5},"editor_notices":[],"footnotes":"","jetpack_post_was_ever_published":false},"categories":[125],"tags":[],"rbc_tl_platform":[131],"rbc_tl_newsletter":[],"rbc_tl_content_type":[132],"rbc_tl_author":[179],"class_list":["post-8858","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ai-technology-and-innovation","rbc_tl_platform-disruptors","rbc_tl_content_type-podcast","rbc_tl_author-rbc-thought-leadership"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Canada&#039;s Biotech Challenge - RBC Thought Leadership<\/title>\n<meta name=\"description\" content=\"Canadian medical research has produced breakthrough after breakthrough. 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